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[Reduction of voluntary alcohol consumption under the effects of prolonged-action zinc]
[Article in Russian]
Skal'nyi AV, Kukhtina EN, Ol'khovskaia IP, Glushchenko NN.
It was revealed that an involuntary rats' intoxication with 10% ethanol solution during 8 months caused a reduction of zinc content in the brain. A subcutaneous depot administration of highly dispersed zinc powder in a dose of 5 mg/kg reduced ethanol consumption under conditions of free choice for two weeks. This effect of the preparation was associated with normalization of zinc content and increase of a malondialdehyde level in the brain.
PMID: 1391896 [PubMed - indexed for MEDLINE]
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