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[The role of oxygen in the inhibition of Escherichia coli respiration by copper ions]
[Article in Russian]
Lebedev VS, Veselovskii AV, Fedorov IuI.
Effect of Cu2+ on E. coli respiration and the role of oxygen in toxic action of copper has been studied. Stimulation of respiration is observed at initial time after introduction of Cu2+. It is based on a nonspecific cell response to membrane damage. After finishing of transitory processes, Cu2+ influenced respiration by noncompetitive inhibition, i.e. copper-sensitive enzyme can be oxygenated or nonoxygenated, and only the latter form of the enzyme is inhibited.
PMID: 2273187 [PubMed - indexed for MEDLINE]
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