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[Role of microviscosity of the lipid phase of microsomal membranes in regulation of enzymatic activity of glucose-6-phosphatase under microsomal modifications in vivo and in vitro]
[Article in Russian]
Burlakova EB, Gvakhariia VO, Glushchenko NN, Dupin A.
The changes in microviscosity of the lipid phase of microsomal membranes under microsomal modification in vivo and in vitro were studied. It was shown that in intact microsome lipids there occur five thermo-induced structural transitions within the temperature range of 5--50 degrees. Delipidation of microsomes results in a shift in structural transitions temperature. Based on the literary and own data it was assumed that the breaks on the Arrhenius plots for glucose-6-phosphatase (EC 3.1.3.9) activity are due to phase-structural changes of microsomal lipids.
PMID: 6246968 [PubMed - indexed for MEDLINE]
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